The University of Tal Afar family, represented by its President, Prof. Dr. Abdul Aziz Ahmed Aziz, extends its sincere congratulations to Professor Ashraf Raad Salem on obtaining his PhD in Medicinal Chemistry.
His doctoral thesis, entitled “Study the effect of polycyclic aromatic hydrocarbons on the allele frequency (Arg72Pro polymorphism) of the Tp53 gene, and its relationship with some antioxidant parameters in a sample of traffic police from Baghdad City,” was discussed in the discussion hall at Al-Nahrain University, College of Medicine, Department of Medicinal Chemistry, under the supervision of Prof. Dr. Istabraq Abdul Rasoul Al-Wasiti.
The study involved drawing blood samples from traffic police officers in Baghdad, who were divided into two groups:
The first group consisted of traffic police officers deployed at the busiest intersections in Baghdad.
The second group included traffic police officers who perform their duties within closed buildings (Baghdad Traffic Police Directorates and Sectors).
This study also included measuring pollutant levels in the blood serum of police volunteers, namely aromatic hydrocarbons emitted from vehicle exhausts and diesel engines. It also included determining the allelic frequency of the Arg72Pro SNP within the TP53 gene and estimating some key oxidative and antioxidant determinants.
The aim of this study was to observe the difference in PAH levels between the two main study groups and to identify the genetic variant of the three Arg72Pro polymorphisms most resistant to the harmful effects of these pollutants by comparing the results of different biomarkers across the three genetic variants.